PRA International is one of the world's leading global clinical development organizations, with approximately 2,500 employees working from offices in North America, Europe, South America, Africa, Australia and Asia. PRA International is an ISO 9001:2000 registered company. PRA International is among industry leaders in providing clinical, operational and consultative support in the development of respiratory treatments. Its respiratory portfolio includes leukotriene modifiers, inhaled and nasal corticosteroids, anticholinergic agents, phosphodiesterase inhibitors, mast-cell stabilizers, vascular adhesion molecule blockers and antihistamines. Its cardiovascular clinical development spans a range of services from clinical development planning and clinical trial applications to the conduct of phase 1-4 trials throughout the world. PRA International is headquartered in Reston, Va.